Validation of (64)Cu-ATSM damaging DNA via high-LET Auger electron emission

Radioactive copper (II) (diacetyl-bis N4-methylthiosemicarbazone) (Cu-ATSM) isotopes were originally developed for the imaging of hypoxia in tumors. Because the decay of a (64)Cu atom is emitting not only positrons but also Auger electrons, this radionuclide has great potential as a theranostic agen...

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Detalhes bibliográficos
Publicado no:J Radiat Res
Main Authors: McMillan, Dayton D., Maeda, Junko, Bell, Justin J., Genet, Matthew D., Phoonswadi, Garrett, Mann, Kelly A., Kraft, Susan L., Kitamura, Hisashi, Fujimori, Akira, Yoshii, Yukie, Furukawa, Takako, Fujibayashi, Yasuhisa, Kato, Takamitsu A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4577009/
https://ncbi.nlm.nih.gov/pubmed/26251463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jrr/rrv042
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