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Disruption of astrocyte-neuron cholesterol cross talk affects neuronal function in Huntington's disease
In the adult brain, neurons require local cholesterol production, which is supplied by astrocytes through apoE-containing lipoproteins. In Huntington's disease (HD), such cholesterol biosynthesis in the brain is severely reduced. Here we show that this defect, occurring in astrocytes, is detrim...
Gorde:
| Argitaratua izan da: | Cell Death Differ |
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| Egile Nagusiak: | , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Nature Publishing Group
2015
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4356339/ https://ncbi.nlm.nih.gov/pubmed/25301063 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2014.162 |
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