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CG100649, a novel COX-2 inhibitor, inhibits colorectal adenoma and tumor growth in mouse models

Nonsteroidal anti-inflammatory drugs (NSAIDs) and selective cyclooxygenase-2 (COX-2) inhibitors (COXIBs) can reduce the risk of developing colorectal cancer (CRC) and are being considered for use as adjuvant therapy for treatment of CRC patients. However, long-term use of most NSAIDs, except aspirin...

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Publicat a:Invest New Drugs
Autors principals: Kim, Sun-Hee, Margalit, Ofer, Katoh, Hiroshi, Wang, Dingzhi, Wu, Hong, Xia, Dianren, Holla, Vijaykumar R., Yang, Peiying, DuBois, Raymond N.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356209/
https://ncbi.nlm.nih.gov/pubmed/25085205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10637-014-0144-z
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