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Prostaglandin E(2) promotes intestinal tumor growth via DNA methylation

Although DNA methylation is one of the critical ways for silencing tumor suppressor and DNA repair genes during tumor initiation and progression, the mechanisms underlying DNA methylation in cancer remain unclear. Here we show that prostaglandin E(2) (PGE(2)) silences certain tumor suppressor and DN...

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Detalhes bibliográficos
Main Authors: Xia, Dianren, Wang, Dingzhi, Kim, Sun-Hee, Katoh, Hiroshi, DuBois, Raymond N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3274627/
https://ncbi.nlm.nih.gov/pubmed/22270723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2608
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