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Prostaglandin E(2) promotes intestinal tumor growth via DNA methylation

Although DNA methylation is one of the critical ways for silencing tumor suppressor and DNA repair genes during tumor initiation and progression, the mechanisms underlying DNA methylation in cancer remain unclear. Here we show that prostaglandin E(2) (PGE(2)) silences certain tumor suppressor and DN...

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Autors principals: Xia, Dianren, Wang, Dingzhi, Kim, Sun-Hee, Katoh, Hiroshi, DuBois, Raymond N.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3274627/
https://ncbi.nlm.nih.gov/pubmed/22270723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2608
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