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In Vivo Role of TLR2 and MyD88 Signaling in Eliciting Innate Immune Responses in Staphylococcal Endophthalmitis

PURPOSE. The purpose of this study was to investigate the protective mechanisms evoked by TLR2 and MyD88 signaling in bacterial endophthalmitis in vivo. METHODS. Endophthalmitis was induced in wild-type (WT), TLR2(−/−), MyD88(−/−), and Cnlp(−/−) mice by intravitreal injections of a laboratory strain...

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發表在:Invest Ophthalmol Vis Sci
Main Authors: Talreja, Deepa, Singh, Pawan Kumar, Kumar, Ashok
格式: Artigo
語言:Inglês
出版: The Association for Research in Vision and Ophthalmology 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356198/
https://ncbi.nlm.nih.gov/pubmed/25678692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.14-16087
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