Allosteric signalling in the outer membrane translocation domain of PapC usher

PapC ushers are outer-membrane proteins enabling assembly and secretion of P pili in uropathogenic E. coli. Their translocation domain is a large β-barrel occluded by a plug domain, which is displaced to allow the translocation of pilus subunits across the membrane. Previous studies suggested that t...

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Publicat a:eLife
Autors principals: Farabella, Irene, Pham, Thieng, Henderson, Nadine S, Geibel, Sebastian, Phan, Gilles, Thanassi, David G, Delcour, Anne H, Waksman, Gabriel, Topf, Maya
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2014
Matèries:
Biophysics and Structural Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356140/
https://ncbi.nlm.nih.gov/pubmed/25271373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.03532
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