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Risk of Anaphylaxis with Repeated Courses of Rasburicase: A Research on Adverse Drug Events and Reports (RADAR) Project

BACKGROUND: Rasburicase, a recombinant urate oxidase, is used to rapidly metabolize uric acid in patients with hyperuricaemia. Rasburicase is an immunogenic therapeutic protein, which has been shown to elicit antibody response in 64 % of healthy volunteers within 1–6 weeks after the initial course,...

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Dettagli Bibliografici
Pubblicato in:Drug Saf
Autori principali: Allen, Katherine C., Champlain, Amanda H., Cotliar, Jonathan A., Belknap, Steven M., West, Dennis P., Mehta, Jayesh, Trifilio, Steven M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355936/
https://ncbi.nlm.nih.gov/pubmed/25566825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s40264-014-0255-7
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