DNA end binding activity and Ku70/80 heterodimer expression in human colorectal tumor

AIM: To determine the DNA binding activity and protein levels of the Ku70/80 heterodimer, the functional mediator of the NHEJ activity, in human colorectal carcinogenesis. METHODS: The Ku70/80 DNA-binding activity was determined by electrophoretic mobility shift assays in 20 colon adenoma and 15 col...

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Detalles Bibliográficos
Publicado en:World J Gastroenterol
Main Authors: Mazzarelli, Paola, Parrella, Paola, Seripa, Davide, Signori, Emanuela, Perrone, Giuseppe, Rabitti, Carla, Borzomati, Domenico, Gabbrielli, Armando, Matera, Maria Giovanna, Gravina, Carolina, Caricato, Marco, Poeta, Maria Luana, Rinaldi, Monica, Valeri, Sergio, Coppola, Roberto, Fazio, Vito Michele
Formato: Artigo
Idioma:Inglês
Publicado: Baishideng Publishing Group Inc 2005
Assuntos:
Brief Reports
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355768/
https://ncbi.nlm.nih.gov/pubmed/16425368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v11.i42.6694
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