Angiostatic treatment prior to chemo- or photodynamic therapy improves anti-tumor efficacy

Tumor vasculature is known to be poorly organized leading to increased leakage of molecules to the extravascular space. This process can potentially increase interstitial fluid pressure impairing intra-tumoral blood flow and oxygen supply, and can affect drug uptake. Anti-angiogenic therapies are be...

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Vydáno v:Sci Rep
Hlavní autoři: Weiss, Andrea, Bonvin, Débora, Berndsen, Robert H., Scherrer, Edoardo, Wong, Tse J., Dyson, Paul J., Griffioen, Arjan W., Nowak-Sliwinska, Patrycja
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355632/
https://ncbi.nlm.nih.gov/pubmed/25758612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08990
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