Expression of ligands for Siglec-8 and Siglec-9 in human airways and airway cells

BACKGROUND: Balanced activation and inhibition of the immune system ensures pathogen clearance while avoiding hyperinflammation. Siglecs, sialic acid binding proteins found on subsets of immune cells, often inhibit inflammation: Siglec-8 on eosinophils and Siglec-9 on neutrophils engage sialoglycan...

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Pubblicato in:J Allergy Clin Immunol
Autori principali: Jia, Yi, Yu, Huifeng, Fernandes, Steve M., Wei, Yadong, Gonzalez-Gil, Anabel, Motari, Mary G., Vajn, Katarina, Stevens, Whitney W., Peters, Anju T., Bochner, Bruce S., Kern, Robert C., Schleimer, Robert P., Schnaar, Ronald L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355580/
https://ncbi.nlm.nih.gov/pubmed/25747723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2015.01.004
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