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ISOLATION, IDENTIFICATION AND CHARACTERIZATION OF THE HUMAN AIRWAY LIGAND FOR THE EOSINOPHIL AND MAST CELL IMMUNOINHIBITORY RECEPTOR SIGLEC-8

BACKGROUND: The immunoinhibitory receptor Siglec-8 on the surface of human eosinophils and mast cells binds to sialic acid-containing ligands in the local milieu resulting in eosinophil apoptosis, inhibition of mast cell degranulation and suppression of inflammation. Siglec-8 ligands were found on p...

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Detalhes bibliográficos
Publicado no:J Allergy Clin Immunol
Main Authors: Gonzalez-Gil, Anabel, Li, T. August, Porell, Ryan N., Fernandes, Steve M., Tarbox, Haley E., Lee, Hyun Sil, Aoki, Kazuhiro, Tiemeyer, Michael, Kim, Jean, Schnaar, Ronald L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7876160/
https://ncbi.nlm.nih.gov/pubmed/32791164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2020.08.001
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