Lysine-Specific Demethylase 2 Suppresses Lipid Influx and Metabolism in Hepatic Cells

Cells link environmental fluctuations, such as nutrition, to metabolic remodeling. Epigenetic factors are thought to be involved in such cellular processes, but the molecular basis remains unclear. Here we report that the lysine-specific demethylase 2 (LSD2) suppresses the flux and metabolism of lip...

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Veröffentlicht in:Mol Cell Biol
Hauptverfasser: Nagaoka, Katsuya, Hino, Shinjiro, Sakamoto, Akihisa, Anan, Kotaro, Takase, Ryuta, Umehara, Takashi, Yokoyama, Shigeyuki, Sasaki, Yutaka, Nakao, Mitsuyoshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355535/
https://ncbi.nlm.nih.gov/pubmed/25624347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01404-14
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