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USP7 Cooperates with SCML2 To Regulate the Activity of PRC1

USP7 is a protein deubiquitinase with an essential role in development. Here, we provide evidence that USP7 regulates the activity of Polycomb repressive complex 1 (PRC1) in coordination with SCML2. There are six versions of PRC1 defined by the association of one of the PCGF homologues (PCGF1 to PCG...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Cell Biol
Hauptverfasser: Lecona, Emilio, Narendra, Varun, Reinberg, Danny
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355532/
https://ncbi.nlm.nih.gov/pubmed/25605328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01197-14
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