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Polycomb Protein SCML2 Regulates the Cell Cycle by Binding and Modulating CDK/CYCLIN/p21 Complexes

Polycomb group (PcG) proteins are transcriptional repressors of genes involved in development and differentiation, and also maintain repression of key genes involved in the cell cycle, indirectly regulating cell proliferation. The human SCML2 gene, a mammalian homologue of the Drosophila PcG protein...

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Detalhes bibliográficos
Main Authors: Lecona, Emilio, Rojas, Luis Alejandro, Bonasio, Roberto, Johnston, Andrew, Fernández-Capetillo, Oscar, Reinberg, Danny
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3866099/
https://ncbi.nlm.nih.gov/pubmed/24358021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001737
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