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Regulation of Sterol Transport between Membranes and NPC2()

Niemann-Pick disease type C (NPC) is caused by defects in either the NPC1 or NPC2 gene and is characterized by accumulation of cholesterol and glycolipids in the late endosome/lysosome compartment. NPC2 is an intralysosomal protein that binds cholesterol in vitro. Previous studies demonstrated rapid...

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書目詳細資料
發表在:Biochemistry
Main Authors: Xu, Zhi, Farver, William, Kodukula, Sarala, Storch, Judith
格式: Artigo
語言:Inglês
出版: 2008
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355403/
https://ncbi.nlm.nih.gov/pubmed/18823126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi801328u
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