Novel daidzein analogs enhance osteogenic activity of bone marrow-derived mesenchymal stem cells and adipose-derived stromal/stem cells through estrogen receptor dependent and independent mechanisms

INTRODUCTION: Osteoporosis is a disease characterized by low bone mineral density (BMD) and increased risk of fractures. Studies have demonstrated the use of phytoestrogens, or plant-derived estrogens, such as genistein and daidzein, to effectively increase osteogenic activity of bone marrow-derived...

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Détails bibliographiques
Publié dans:Stem Cell Res Ther
Auteurs principaux: Strong, Amy L, Ohlstein, Jason F, Jiang, Quan, Zhang, Qiang, Zheng, Shilong, Boue, Stephen M, Elliott, Steven, Gimble, Jeffrey M, Burow, Matthew E, Wang, Guangdi, Bunnell, Bruce A
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2014
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355363/
https://ncbi.nlm.nih.gov/pubmed/25168698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/scrt493
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