PPARγ depletion stimulates Nox4 expression and human pulmonary artery smooth muscle cell proliferation

Hypoxia stimulates pulmonary hypertension (PH) in part by increasing the proliferation of pulmonary vascular wall cells. Recent evidence suggests that signaling events involved in hypoxia-induced cell proliferation include sustained nuclear factor-kappaB (NF-κB) activation, increased NADPH oxidase 4...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Free Radic Biol Med
Auteurs principaux: Bijli, Kaiser M., Kleinhenz, Jennifer M., Murphy, Tamara C., Kang, Bum-Yong, Adesina, Sherry E., Sutliff, Roy L., Hart, C. Michael
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355175/
https://ncbi.nlm.nih.gov/pubmed/25557278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2014.12.019
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires