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Spectacle: fast chromatin state annotation using spectral learning
Epigenomic data from ENCODE can be used to associate specific combinations of chromatin marks with regulatory elements in the human genome. Hidden Markov models and the expectation-maximization (EM) algorithm are often used to analyze epigenomic data. However, the EM algorithm can have overfitting p...
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| Publicado no: | Genome Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4355146/ https://ncbi.nlm.nih.gov/pubmed/25786205 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-015-0598-0 |
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