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A novel fluorescence-based biosynthetic trafficking method provides pharmacologic evidence that PI4-kinase IIIα is important for protein trafficking from the endoplasmic reticulum to the plasma membrane

BACKGROUND: Biosynthetic trafficking of receptors and other membrane-associated proteins from the endoplasmic reticulum (ER) to the plasma membrane (PM) underlies the capacity of these proteins to participate in crucial cellular roles. Phosphoinositides have been shown to mediate distinct biological...

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Publicat a:BMC Cell Biol
Autors principals: Bryant, Kirsten L, Baird, Barbara, Holowka, David
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4355129/
https://ncbi.nlm.nih.gov/pubmed/25886792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12860-015-0049-5
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