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CXCL13 responsiveness but not CXCR5 expression by late transitional B cells initiates splenic white pulp formation
Secondary lymphoid organs (SLO) provide the structural framework for co-concentration of antigen and antigen-specific lymphocytes required for an efficient adaptive immune system. The spleen is the primordial SLO, and evolved concurrently with Ig/TCR:pMHC-based adaptive immunity. The earliest cellul...
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| Veröffentlicht in: | J Immunol |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4355030/ https://ncbi.nlm.nih.gov/pubmed/25662995 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401905 |
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