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ANTIBODY-CYTOKINE FUSION PROTEINS FOR TREATMENT OF CANCER: ENGINEERING CYTOKINES FOR IMPROVED EFFICACY AND SAFETY

The true potential of cytokine therapies in cancer treatment is limited by the inability to deliver optimal concentrations into tumor sites due to dose-limiting systemic toxicities. To maximize the efficacy of cytokine therapy, recombinant antibody-cytokine fusion proteins have been constructed by a...

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Dettagli Bibliografici
Pubblicato in:Semin Oncol
Autori principali: Young, Patricia A., Morrison, Sherie L., Timmerman, John M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4354941/
https://ncbi.nlm.nih.gov/pubmed/25440607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.seminoncol.2014.08.002
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