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ANTIBODY-CYTOKINE FUSION PROTEINS FOR TREATMENT OF CANCER: ENGINEERING CYTOKINES FOR IMPROVED EFFICACY AND SAFETY

The true potential of cytokine therapies in cancer treatment is limited by the inability to deliver optimal concentrations into tumor sites due to dose-limiting systemic toxicities. To maximize the efficacy of cytokine therapy, recombinant antibody-cytokine fusion proteins have been constructed by a...

詳細記述

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書誌詳細
出版年:Semin Oncol
主要な著者: Young, Patricia A., Morrison, Sherie L., Timmerman, John M.
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4354941/
https://ncbi.nlm.nih.gov/pubmed/25440607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.seminoncol.2014.08.002
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