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ANTIBODY-CYTOKINE FUSION PROTEINS FOR TREATMENT OF CANCER: ENGINEERING CYTOKINES FOR IMPROVED EFFICACY AND SAFETY

The true potential of cytokine therapies in cancer treatment is limited by the inability to deliver optimal concentrations into tumor sites due to dose-limiting systemic toxicities. To maximize the efficacy of cytokine therapy, recombinant antibody-cytokine fusion proteins have been constructed by a...

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Bibliographische Detailangaben
Veröffentlicht in:Semin Oncol
Hauptverfasser: Young, Patricia A., Morrison, Sherie L., Timmerman, John M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4354941/
https://ncbi.nlm.nih.gov/pubmed/25440607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.seminoncol.2014.08.002
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