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Soluble Interleukin-15 Complexes Are Generated In Vivo by Type I Interferon Dependent and Independent Pathways

Interleukin (IL)-15 associates with IL-15Rα on the cell surface where it can be cleaved into soluble cytokine/receptor complexes that have the potential to stimulate CD8 T cells and NK cells. Unfortunately, little is known about the in vivo production of soluble IL-15Rα/IL-15 complexes (sIL-15 compl...

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Publicat a:PLoS One
Autors principals: Anthony, Scott M., Howard, Megan E., Hailemichael, Yared, Overwijk, Willem W., Schluns, Kimberly S.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4354909/
https://ncbi.nlm.nih.gov/pubmed/25756182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120274
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