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The Ribosome Biogenesis Factor Nol11 Is Required for Optimal rDNA Transcription and Craniofacial Development in Xenopus

The production of ribosomes is ubiquitous and fundamental to life. As such, it is surprising that defects in ribosome biogenesis underlie a growing number of symptomatically distinct inherited disorders, collectively called ribosomopathies. We previously determined that the nucleolar protein, NOL11,...

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Détails bibliographiques
Publié dans:PLoS Genet
Auteurs principaux: Griffin, John N., Sondalle, Samuel B., del Viso, Florencia, Baserga, Susan J., Khokha, Mustafa K.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4354908/
https://ncbi.nlm.nih.gov/pubmed/25756904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005018
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