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Paired Box 9 (PAX9), the RNA polymerase II transcription factor, regulates human ribosome biogenesis and craniofacial development

Dysregulation of ribosome production can lead to a number of developmental disorders called ribosomopathies. Despite the ubiquitous requirement for these cellular machines used in protein synthesis, ribosomopathies manifest in a tissue-specific manner, with many affecting the development of the face...

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Bibliografiske detaljer
Udgivet i:PLoS Genet
Main Authors: Farley-Barnes, Katherine I., Deniz, Engin, Overton, Maya M., Khokha, Mustafa K., Baserga, Susan J.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7437866/
https://ncbi.nlm.nih.gov/pubmed/32813698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008967
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