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Effects of the NK(1) Antagonist, Aprepitant, on Response to Oral and Intranasal Oxycodone in Prescription Opioid Abusers
Preclinical studies suggest that the NK(1) receptor may modulate the response to opioids, with NK(1) inactivation leading to decreased opioid reinforcement, tolerance and withdrawal. Aprepitant is a selective NK(1) antagonist currently marketed for clinical use as an anti-emetic. This 6-week inpatie...
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| Izdano u: | Addict Biol |
|---|---|
| Glavni autori: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2012
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4354863/ https://ncbi.nlm.nih.gov/pubmed/22260216 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1369-1600.2011.00419.x |
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