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Evaluation of tradipitant, a selective NK1 antagonist, on response to oxycodone in humans

RATIONALE: Preclinical studies demonstrate that the NK1 receptor is involved in opioid reinforcement and withdrawal expression. Few studies have examined the impact of treatment with NK1 antagonists on opioid response in humans. OBJECTIVE: To explore the potential for a selective NK1 antagonist, tra...

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Bibliographische Detailangaben
Veröffentlicht in:Psychopharmacology (Berl)
Hauptverfasser: Coe, Marion A., Lofwall, Michelle R., Vessels, Victoria, Nuzzo, Paul A., Walsh, Sharon L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer Berlin Heidelberg 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8120018/
https://ncbi.nlm.nih.gov/pubmed/33988725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-021-05814-x
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