Magnetic resonance hypointensive signal primarily originates from extracellular iron particles in the long-term tracking of mesenchymal stem cells transplanted in the infarcted myocardium

PURPOSE: The long-lasting hypointensities in cardiac magnetic resonance (CMR) were believed to originate from superparamagnetic iron oxide (SPIO)-engulfed macrophages during long-term stem cell tracking. However, the iron clearance capacity of the ischemic heart was limited. Therefore, we speculated...

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Dettagli Bibliografici
Pubblicato in:Int J Nanomedicine
Autori principali: Huang, Zheyong, Li, Chenguang, Yang, Shan, Xu, Jianfeng, Shen, Yunli, Xie, Xinxing, Dai, Yuxiang, Lu, Hao, Gong, Hui, Sun, Aijun, Qian, Juying, Ge, Junbo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2015
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Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4354691/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S77858
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