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Preparation and Respirometric Assessment of Mitochondria Isolated from Skeletal Muscle Tissue Obtained by Percutaneous Needle Biopsy

Respirometric profiling of isolated mitochondria is commonly used to investigate electron transport chain function. We describe a method for obtaining samples of human Vastus lateralis, isolating mitochondria from minimal amounts of skeletal muscle tissue, and plate based respirometric profiling usi...

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Bibliografiske detaljer
Udgivet i:J Vis Exp
Main Authors: Bharadwaj, Manish S., Tyrrell, Daniel J., Lyles, Mary F., Demons, Jamehl L., Rogers, George W., Molina, Anthony J. A.
Format: Artigo
Sprog:Inglês
Udgivet: MyJove Corporation 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4354623/
https://ncbi.nlm.nih.gov/pubmed/25741892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/52350
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