The Neuromuscular Junction: Measuring Synapse Size, Fragmentation and Changes in Synaptic Protein Density Using Confocal Fluorescence Microscopy

The neuromuscular junction (NMJ) is the large, cholinergic relay synapse through which mammalian motor neurons control voluntary muscle contraction. Structural changes at the NMJ can result in neurotransmission failure, resulting in weakness, atrophy and even death of the muscle fiber. Many studies...

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Bibliografiske detaljer
Udgivet i:J Vis Exp
Main Authors: Tse, Nigel, Morsch, Marco, Ghazanfari, Nazanin, Cole, Louise, Visvanathan, Archunan, Leamey, Catherine, Phillips, William D.
Format: Artigo
Sprog:Inglês
Udgivet: MyJove Corporation 2014
Fag:
Neuroscience
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4354481/
https://ncbi.nlm.nih.gov/pubmed/25590231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/52220
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