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Cell death in response to antimetabolites directed at ribonucleotide reductase and thymidylate synthase

New agent development, mechanistic understanding, and combinatorial partnerships with known and novel modalities continue to be important in the study of pancreatic cancer and its improved treatment. In this study, known antimetabolite drugs such as gemcitabine (ribonucleotide reductase inhibitor) a...

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Publicat a:Onco Targets Ther
Autors principals: Asuncion Valenzuela, Malyn M, Castro, Imilce, Gonda, Amber, Diaz Osterman, Carlos J, Jutzy, Jessica M, Aspe, Jonathan R, Khan, Salma, Neidigh, Jonathan W, Wall, Nathan R
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4354452/
https://ncbi.nlm.nih.gov/pubmed/25767396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S79647
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