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Cell death in response to antimetabolites directed at ribonucleotide reductase and thymidylate synthase

New agent development, mechanistic understanding, and combinatorial partnerships with known and novel modalities continue to be important in the study of pancreatic cancer and its improved treatment. In this study, known antimetabolite drugs such as gemcitabine (ribonucleotide reductase inhibitor) a...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Principais autores: Asuncion Valenzuela, Malyn M, Castro, Imilce, Gonda, Amber, Diaz Osterman, Carlos J, Jutzy, Jessica M, Aspe, Jonathan R, Khan, Salma, Neidigh, Jonathan W, Wall, Nathan R
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4354452/
https://ncbi.nlm.nih.gov/pubmed/25767396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S79647
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