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Nuclear-encoded factors involved in post-transcriptional processing and modification of mitochondrial tRNAs in human disease
The human mitochondrial genome (mtDNA) encodes 22 tRNAs (mt-tRNAs) that are necessary for the intraorganellar translation of the 13 mtDNA-encoded subunits of the mitochondrial respiratory chain complexes. Maturation of mt-tRNAs involves 5′ and 3′ nucleolytic excision from precursor RNAs, as well as...
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| Veröffentlicht in: | Front Genet |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Frontiers Media S.A.
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4354410/ https://ncbi.nlm.nih.gov/pubmed/25806043 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2015.00079 |
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