In vitro and in vivo anti-angiogenic activity of girinimbine isolated from Murraya koenigii

Girinimbine is a carbazole alkaloid isolated from the stem bark and root of Murraya koenigii. Here we report that girinimbine is an inhibitor of angiogenic activity both in vitro and in vivo. MTT results showed that girinimbine inhibited proliferation of human umbilical vein endothelial cells, while...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Iman, Venoos, Karimian, Hamed, Mohan, Syam, Hobani, Yahya Hasan, Noordin, Mohamed Ibrahim, Mustafa, Mohd Rais, Noor, Suzita Mohd
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2015
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4354401/
https://ncbi.nlm.nih.gov/pubmed/25767375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S71557
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