In vitro and in vivo anti-angiogenic activity of girinimbine isolated from Murraya koenigii

Girinimbine is a carbazole alkaloid isolated from the stem bark and root of Murraya koenigii. Here we report that girinimbine is an inhibitor of angiogenic activity both in vitro and in vivo. MTT results showed that girinimbine inhibited proliferation of human umbilical vein endothelial cells, while...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Drug Des Devel Ther
Hauptverfasser: Iman, Venoos, Karimian, Hamed, Mohan, Syam, Hobani, Yahya Hasan, Noordin, Mohamed Ibrahim, Mustafa, Mohd Rais, Noor, Suzita Mohd
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove Medical Press 2015
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4354401/
https://ncbi.nlm.nih.gov/pubmed/25767375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S71557
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