Targeting IL-17B–IL-17RB signaling with an anti–IL-17RB antibody blocks pancreatic cancer metastasis by silencing multiple chemokines

Pancreatic cancer has an extremely high mortality rate due to its aggressive metastatic nature. Resolving the underlying mechanisms will be crucial for treatment. Here, we found that overexpression of IL-17B receptor (IL-17RB) strongly correlated with postoperative metastasis and inversely correlate...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Wu, Heng-Hsiung, Hwang-Verslues, Wendy W., Lee, Wen-Hsin, Huang, Chun-Kai, Wei, Pei-Chi, Chen, Chia-Lin, Shew, Jin-Yuh, Lee, Eva Y.-H.P., Jeng, Yung-Ming, Tien, Yu-Wen, Ma, Che, Lee, Wen-Hwa
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2015
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4354366/
https://ncbi.nlm.nih.gov/pubmed/25732306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20141702
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados