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Concurrent Targeting of KRAS and AKT by MiR-4689 Is a Novel Treatment Against Mutant KRAS Colorectal Cancer
KRAS mutations are a major cause of drug resistance to molecular-targeted therapies. Aberrant epidermal growth factor receptor (EGFR) signaling may cause dysregulation of microRNA (miRNA) and gene regulatory networks, which leads to cancer initiation and progression. To address the functional releva...
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發表在: | Mol Ther Nucleic Acids |
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Main Authors: | , , , , , , , , , , , , , , |
格式: | Artigo |
語言: | Inglês |
出版: |
Nature Publishing Group
2015
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4354340/ https://ncbi.nlm.nih.gov/pubmed/25756961 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2015.5 |
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