Concurrent Targeting of KRAS and AKT by MiR-4689 Is a Novel Treatment Against Mutant KRAS Colorectal Cancer

KRAS mutations are a major cause of drug resistance to molecular-targeted therapies. Aberrant epidermal growth factor receptor (EGFR) signaling may cause dysregulation of microRNA (miRNA) and gene regulatory networks, which leads to cancer initiation and progression. To address the functional releva...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Hiraki, Masayuki, Nishimura, Junichi, Takahashi, Hidekazu, Wu, Xin, Takahashi, Yusuke, Miyo, Masaaki, Nishida, Naohiro, Uemura, Mamoru, Hata, Taishi, Takemasa, Ichiro, Mizushima, Tsunekazu, Soh, Jae-Won, Doki, Yuichiro, Mori, Masaki, Yamamoto, Hirofumi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4354340/
https://ncbi.nlm.nih.gov/pubmed/25756961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2015.5
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados