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Functional Significance of Cytochrome P450 1A2 Allelic Variants, P450 1A2*8, *15, and *16 (R456H, P42R, and R377Q)

P450 1A2 is responsible for the metabolism of clinically important drugs and the metabolic activation of environmental chemicals. Genetic variations of P450 1A2 can influence its ability to perform these functions, and thus, this study aimed to characterize the functional significance of three P450...

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Detalhes bibliográficos
Publicado no:Biomol Ther (Seoul)
Main Authors: Lim, Young-Ran, Kim, In-Hyeok, Han, Songhee, Park, Hyoung-Goo, Ko, Mi-Jung, Chun, Young-Jin, Yun, Chul-Ho, Kim, Donghak
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Society of Applied Pharmacology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4354321/
https://ncbi.nlm.nih.gov/pubmed/25767688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4062/biomolther.2015.009
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