Functional Significance of Cytochrome P450 1A2 Allelic Variants, P450 1A2*8, *15, and *16 (R456H, P42R, and R377Q)

P450 1A2 is responsible for the metabolism of clinically important drugs and the metabolic activation of environmental chemicals. Genetic variations of P450 1A2 can influence its ability to perform these functions, and thus, this study aimed to characterize the functional significance of three P450...

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Dettagli Bibliografici
Pubblicato in:Biomol Ther (Seoul)
Autori principali: Lim, Young-Ran, Kim, In-Hyeok, Han, Songhee, Park, Hyoung-Goo, Ko, Mi-Jung, Chun, Young-Jin, Yun, Chul-Ho, Kim, Donghak
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Korean Society of Applied Pharmacology 2015
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4354321/
https://ncbi.nlm.nih.gov/pubmed/25767688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4062/biomolther.2015.009
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