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Deleting maternal Gtl2 leads to growth enhancement and decreased expression of stem cell markers in teratoma

The distal region of mouse chromosome 12 harbors the Dlk1–Dio3 domain, is essential for normal development and encodes maternally expressed noncoding RNAs (ncRNAs), including Gtl2 as well as paternally expressed proteins.Gtl2 works as a tumor suppressor in several types of human cancer cell lines; h...

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Detalles Bibliográficos
Publicado en:J Reprod Dev
Main Authors: TAKAHASHI, Nozomi, YAMAGUCHI, Eito, KAWABATA, Yukiko, KONO, Tomohiro
Formato: Artigo
Idioma:Inglês
Publicado: The Society for Reproduction and Development 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4354225/
https://ncbi.nlm.nih.gov/pubmed/25355544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1262/jrd.2014-089
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