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The nucleolar protein nucleophosmin is essential for autophagy induced by inhibiting Pol I transcription
Various cellular stresses activate autophagy, which is involved in lysosomal degradation of cytoplasmic materials for maintaining nutrient homeostasis and eliminating harmful components. Here, we show that RNA polymerase I (Pol I) transcription inhibition induces nucleolar disruption and autophagy....
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4354046/ https://ncbi.nlm.nih.gov/pubmed/25754892 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep08903 |
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