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Formation of in vivo complexes between the TAL1 and E2A polypeptides of leukemic T cells.

Tumor-specific activation of the TAL1 gene occurs in approximately 25% of patients with T-cell acute lymphoblastic leukemia (T-ALL). The TAL1 gene products possess a basic helix-loop-helix (bHLH) domain that interacts in vitro with the bHLH proteins (E12 and E47) encoded by the E2A locus. We have no...

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Bibliografski detalji
Glavni autori: Hsu, H L, Wadman, I, Baer, R
Format: Artigo
Jezik:Inglês
Izdano: 1994
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC43539/
https://ncbi.nlm.nih.gov/pubmed/8159721
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