Aberrant DNA methylation of imprinted loci in hepatocellular carcinoma and after in vitro exposure to common risk factors

BACKGROUND: Hepatocellular carcinoma (HCC) is among the most frequent human malignancies and a major cause of cancer-related death worldwide. It is characterized by late detection and fast progression, and it is believed that epigenetic disruption may be one of the molecular mechanisms leading to he...

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Veröffentlicht in:Clin Epigenetics
Hauptverfasser: Lambert, Marie-Pierre, Ancey, Pierre-Benoit, Esposti, Davide Degli, Cros, Marie-Pierre, Sklias, Athena, Scoazec, Jean-Yves, Durantel, David, Hernandez-Vargas, Hector, Herceg, Zdenko
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
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Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4353474/
https://ncbi.nlm.nih.gov/pubmed/25755686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-015-0053-9
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