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Crystal structure of afadin PDZ domain–nectin-3 complex shows the structural plasticity of the ligand-binding site
Afadin, a scaffold protein localized in adherens junctions (AJs), links nectins to the actin cytoskeleton. Nectins are the major cell adhesion molecules of AJs. At the initial stage of cell–cell junction formation, the nectin–afadin interaction plays an indispensable role in AJ biogenesis via recrui...
Shranjeno v:
| izdano v: | Protein Sci |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BlackWell Publishing Ltd
2015
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4353363/ https://ncbi.nlm.nih.gov/pubmed/25534554 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2628 |
| Oznake: |
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