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Construction of a chimeric lysin Ply187N-V12C with extended lytic activity against staphylococci and streptococci

Developing chimeric lysins with a wide lytic spectrum would be important for treating some infections caused by multiple pathogenic bacteria. In the present work, a novel chimeric lysin (Ply187N-V12C) was constructed by fusing the catalytic domain (Ply187N) of the bacteriophage lysin Ply187 with the...

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Detalhes bibliográficos
Publicado no:Microb Biotechnol
Main Authors: Dong, Qiuhua, Wang, Jing, Yang, Hang, Wei, Cuihua, Yu, Junping, Zhang, Yun, Huang, Yanling, Zhang, Xian-En, Wei, Hongping
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4353335/
https://ncbi.nlm.nih.gov/pubmed/25219798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/1751-7915.12166
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