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Roadblocks to success for RNA CARs in solid tumors
While CAR therapy has begun to demonstrate efficacy, cell-engineering techniques that result in permanent genomic modification carry several safety concerns. CAR expression driven by RNA creates a platform for delivery of highly-active cell therapy while avoiding long-term CAR-driven toxicity. Using...
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| Pubblicato in: | Oncoimmunology |
|---|---|
| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Taylor & Francis
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4353174/ https://ncbi.nlm.nih.gov/pubmed/25964863 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21624011.2014.962974 |
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