Загрузка...

Roadblocks to success for RNA CARs in solid tumors

While CAR therapy has begun to demonstrate efficacy, cell-engineering techniques that result in permanent genomic modification carry several safety concerns. CAR expression driven by RNA creates a platform for delivery of highly-active cell therapy while avoiding long-term CAR-driven toxicity. Using...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Oncoimmunology
Главные авторы: Singh, Nathan, Barrett, David M, Grupp, Stephan A
Формат: Artigo
Язык:Inglês
Опубликовано: Taylor & Francis 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4353174/
https://ncbi.nlm.nih.gov/pubmed/25964863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21624011.2014.962974
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!