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Reversal of natural killer cell exhaustion by TIM-3 blockade
Natural killer (NK) cells are innate immune cells that become progressively exhausted in advanced stage cancer, crippling their ability to execute antitumor functions. We previously characterized the nature of NK cell exhaustion in metastatic melanoma patients, reporting a correlation with high expr...
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| 發表在: | Oncoimmunology |
|---|---|
| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Taylor & Francis
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4353130/ https://ncbi.nlm.nih.gov/pubmed/25964857 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21624011.2014.946365 |
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