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Reversal of natural killer cell exhaustion by TIM-3 blockade

Natural killer (NK) cells are innate immune cells that become progressively exhausted in advanced stage cancer, crippling their ability to execute antitumor functions. We previously characterized the nature of NK cell exhaustion in metastatic melanoma patients, reporting a correlation with high expr...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Gallois, Anne, Silva, Ines, Osman, Iman, Bhardwaj, Nina
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4353130/
https://ncbi.nlm.nih.gov/pubmed/25964857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21624011.2014.946365
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