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Subverting the adaptive immune resistance mechanism to improve clinical responses to immune checkpoint blockade therapy
The correlation between tumor-infiltrating lymphocyte (TIL)-expression of programmed cell death ligand 1 (PD-L1) and clinical responsiveness to the PD-1 blocking antibody nivolumab implicates adaptive immune evasion mechanisms in cancer. We review our findings that tumor cell PD-L1 expression is ind...
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| Publié dans: | Oncoimmunology |
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| Auteur principal: | |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Taylor & Francis
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4352965/ https://ncbi.nlm.nih.gov/pubmed/25964860 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21624011.2014.954868 |
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